US20160145276A1 - Traceless directing groups in radical

Yuanfei Zhang, Huaiqing Zhao, Min Zhang, Weiping Su, Carboxylic Acids as Traceless Directing Groups for the Rhodium(III)‐Catalyzed Decarboxylative C H Arylation of Thiophenes, Angewandte Chemie, 10.1002/ange.201411701, 127, 12, (3888-3892), (2015). Group members - Alabugin Group at FSU Edgar earned his bachelor's degree in Chemical Pharmaceutical Biology from Universidad LaSalle in Mexico City. He is currently working on combining stereoelectronics, traceless directing groups, and dynamic covalent chemistry for the design of alkyne cascades towards carbon-rich molecules and materials. Email. Michael Maxwell Filming Location Matching "Cuddington, Buckinghamshire

(16) Traceless Directing-Group Strategy in the Ru-Catalyzed Formal [3 + 3] Annulation of Anilines with Allyl Alcohols: A One-Pot Domino Approach for the Synthesis of Quinolines.

A highly efficient and general protocol for traceless, directed C3-selective C-H borylation of indoles with [Ni(IMes)2] as the catalyst is reported. Activation and borylation of N-H bonds by [Ni(IMes)2] is essential to install a Bpin moiety at the N-position as a traceless directing group, which enables the C3-selective borylation of C-H bonds. Directed Meta-Selective CH Bond Functionalizations

The present disclosure is directed to a traceless directing group in a radical cascade. The chemo- and regioselectivity of the initial attack in skipped oligoalkynes is controlled by a propargyl alkoxy moiety. Radical translocations lead to the boomerang return of radical center to the site of initial attack where it assists to the elimination of the directing functionality via β-scission in

A strategy is reported in which traceless directing groups (TDGs) are used to promote the redox‐neutral Mn I ‐catalyzed regioselective synthesis of N‐heterocycles. Alkyne coupling partners bearing a traceless directing group, which serves as both the chelator and internal oxidant, were used to control the regioselectivity of the annulation reactions. Cobalt-Catalyzed Selective Synthesis of Isoquinolines Abstract Picolinamide has first been employed as a traceless directing group for the cobalt-catalyzed oxidative annulation of benzylamides with alkynes to synthesize isoquinolines through C–H/N–H bonds activation. Oxygen is used as a terminal oxidant. This protocol exhibits good functional group tolerance and excellent regioselectivity.